Interactions of Estrogen- and Thyroid Hormone Receptors on a Progesterone Receptor Estrogen Response Element (ERE) Sequence: a Comparison with the Vitellogenin A2 Consensus ERE
نویسندگان
چکیده
منابع مشابه
Expression of Estrogen and Progesterone Receptors in Papillary Thyroid Carcinoma
Background: Papillary thyroid carcinoma (PTC), occurs mostly in women and sex hormones may play a role in the pathogenesis and clinical course. The objective of this study was to determine the status and prevalence of estrogen and progesterone receptors in PTC with regard to age, gender, tumor size and lymph node involvement. Methods: Immunohistochemical stains were performed on 92 tissue bl...
متن کاملThyroid hormone can increase estrogen-mediated transcription from a consensus estrogen response element in neuroblastoma cells.
Thyroid hormones (T) and estrogens (E) are nuclear receptor ligands with at least two molecular mechanisms of action: (i) relatively slow genomic effects, such as the regulation of transcription by cognate T receptors (TR) and E receptors (ER); and (ii) relatively rapid nongenomic effects, such as kinase activation and calcium release initiated at the membrane by putative membrane receptors. Ge...
متن کاملInteractions of dietary estrogens with human estrogen receptors and the effect on estrogen receptor-estrogen response element complex formation.
Epidemiologic and experimental studies support the hypothesis that dietary estrogens from plant sources (phytoestrogens) may play a role in the prevention of breast and prostate cancer. The molecular mechanisms for such chemopreventive effect are still unclear. We investigated the possibility that phytoestrogens may bind differentially to estrogen receptor proteins (ER[alpha] and ERss) and affe...
متن کاملTranscriptional effects of metal ions on the bovine oxytocin and the thymidine kinase-ERE promoter through the estrogen receptor a in MDA-MB 231 breast cancer cell line
BACKGROUND: Some of metal ions as environmental pollutants show estrogenic activity. This xenostrogenic compounds can be caused carcinogenicity in organs. The mechanism of carcinogenicity of metal ions is not clarified. OBJECTIVES: In this study, we investigated the Transcriptional effects of variety of metal ions on the bovine oxytocin and the thymidine kinase-ERE promoter by estrogen receptor...
متن کاملProtein Surface Comparison Algorithm for Predicting DNA Binding Proteins - Using Estrogen Response Element (ERE) as a Model
In the post-genome era, the structures of protein domains have been published rapidly. Researches have also gained diversity of interests from the structure data, yet only few have concentrated on protein tertiary structure alignment while alignments focused on protein surfaces are even rarer. However, the surface structure of a protein binding motif should be deemed an important factor to dete...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Endocrinology
سال: 1997
ISSN: 0888-8809,1944-9917
DOI: 10.1210/mend.11.11.0003